Brickell Biotech Phase III Primary Axillary Hyperhidrosis Study


Clinically Media enrolled two parallel Phase 3 primary axillary hyperhidrosis studies on schedule. Clinically Media is a group of patient recruitment and retention professionals devoted to empowering individuals to participate in clinical research.

The Details

The Challenge

For the 365 million individuals in the world suffering from hyperhidrosis (excessive sweating), the condition has resulted in occupational, emotional, psychological, social, and physical impairment. In addition, hyperhidrosis is undertreated and underrecognized as a serious disorder negatively impacting the quality of life for both adults and adolescents. According to the American Academy of Dermatology, half of people with hyperhidrosis delay treatment for 10 years or more.

With limited treatments available for hyperhidrosis patients, clinical-stage company Brickell Biotech has been developing a new potential non-invasive treatment focused on axillary hyperhidrosis (excessive underarm sweating). Clinically Media was retained to develop a comprehensive Central Campaign to recruit and enroll two parallel US-based Phase III trials efficiently with qualified adult and pediatric patients.

Additional Challenges Faced

  • COVID-19 (site shutdowns, public’s fear of leaving home)

  • High screen-fail rate

Study Stats

  • 81 Research Sites

  • 700 patients enrolled total

  • 50% patients enrolled via Clinically Media

  • Enrollment was completed on schedule

Clinically Media's Solution


    Data-backed umbrella study branding used across all materials, including both recruitment and patient training/retention materials


    Trackable digital campaign with an emphasis on highly targeted social media advertising


    Intensive prescreening efforts, including an online form and phone screening, and managing a third-party support


    In-depth internal tracking to track referrals all the way through enrollment and study completion


    Consistent, close communication and follow up with research sites allowed us to provide an individualized recruitment strategy for each site


    Collaboration with advocacy groups like the International Hyperhidrosis Society, Google search ads, local advertising, physician outreach

Reached Target

Through advanced IT support and customized solutions, Clinically Media was able to develop a cohesive brand, streamline lead generation, and lessen the burden placed on research sites. As a result, Clinically Media successfully enrolled the study in the anticipated 7-month enrollment period.

Overall Results

  • ~12,600

    Total prequalified referrals

  • ~245

    Total prequalified pediatric referrals


  • 985

    Total screened referrals

  • 339

    Total randomized patients

  • 34.4%

    Randomization rate

They were efficient and nimble in providing both an umbrella recruitment strategy and customized support directly to sites to ensure our aggressive enrollment goal was met.
Clinical Operations Project Manager

Other Services Clinically Media Offers

Coordinator Training Materials

Including mobile apps, video, print manuals, tri-folds

Patient Training Materials

Including diaries, trackers, appointment reminders, videos, tri-folds, mobile apps, and more

Branding and Marketing

Including brand packages, logo design, social media, PR, IR

Patient Recruitment

Including digital, social media, grassroots, and traditional advertising methods

what our Partners say about us

Clinically Media has been a total success with our practice! The one-on-one professionalism and honest dedication to growing our population has been a resounding success. We look forward to our continuing relationship, thank you!

Study Coordinator

Windsor Dermatology/Psoriasis Treatment Center of Central New Jersey

Clinically Media exceeded our expectations in their recruitment support for Brickell’s two Phase 3 trials. They were efficient and nimble in providing both an umbrella recruitment strategy and customized support directly to sites to ensure our aggressive enrollment goal was met.

Clinical Operations, Project Manager

Brickell Biotech

A true partner from the very beginning -- Clinically Media is a go to team for establishing corporate branding and commercialization planning.  Whether our needs be complete website redesign, social media strategy or efficient market research execution, Clinically Media delivers on time, on budget, with quality work and creative recommendations.  I’d highly recommend this team as an extension of your own.

Commercial Marketing


Clinically Media delivered outstanding, high quality creative, visual and graphic web-based solutions within our agreed timelines. I enjoyed collaborating with Victoria and her team, and will definitely consider using their services for future clinical studies. I strongly recommend Clinically Media to other companies.

L. A. Romel

Principal at Lawrence Romel Consulting

Clinically Media’s efficiency and attention to detail contributed to the enrollment success of the Sahara axillary hyperhidrosis study.

Erin Tims, Senior Clinical Director

Candesant Biomedical

Clinically Media did very well and are easy to work with. Will work with them again in the future for sure. And their portal is easy to navigate. Keep doing what you're doing!

James, Study Coordinator

Windsor Dermatology/Eczema and Psoriasis Treatment Centers of NJ

The Clinically Media team is efficient and flexible. They brought new, customized solutions to our recruitment campaign for melasma patients, and they surpassed our goal number of referrals. We enjoyed working with them and hope to work together again in the future.

Dr. Dhawan

Center for Dermatology

We love working with the Clinically Media team. They provide professional, informed marketing advice and analytics, and they always create on-brand and engaging images and captions for Brickell’s social channels.

Chief Marketing Officer

Brickell Biotech

I can't say enough about the quality of work, responsiveness, and flexibility that Clinically Media brought to the project. I hope to have another project that needs Clinically Media's services.

Clinical Operations

Brickell Biotect

Communication was excellent! Worked well with changing a few things to bring in more referrals.

Clinical Research

Hamzavi Dermatology

We are so happy to have partnered with Clinically Media. Working in a small start up environment, we lacked not only resources but expertise. The ideas that CM brought to the table were innovative and fresh, and we saw our boost in enrollment immediately. Victoria and Brenda were not only flexible, but problem solvers -we are grateful to have worked with such a wonderful company.

Prism Study, Parkinson's Disease